Pyridine → HCID 20162879, compound

Participants

Reaction Conditions

Reaction Steps

The amine (42) (490 mg) in dry dichloromethane was cooled to 0° C. and treated with pyridine (211 mg) followed by formic-acetic anhydride (117 mg). The mixture was stirred at 0° C. for 5 minutes then allowed to warm to room temperature. After 1/2 hour the solvent was evaporated and the residue dried in vacuo. The solid was triturated with dry ether, filtered off, and washed with more ether before drying in vacuo to give the product (43) (510 mg) as a white solid. νmax (NUJOL) 3250 br, 1780sh, 1760, 1680sh, 1655 and 1345 cm-1.

Provenance & Evidence