HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 4-Chloro-L-phenylalanine methyl ester hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Chloro-L-phenylalanine | HCID 736190 | — |
| Product | 4-Chloro-L-phenylalanine methyl ester hydrochloride | HCID 23619157 | — |
Reaction Steps
0.14 mol (10 ml, 16.5 grams) of thionyl chloride were dropped at -5° C. into 100 ml of methanol. After addition of 0.11 mole (22 grams) of 4-chlorophenylalanine the mixture was heated under reflux for 15 hours. After drawing off the solvent the white residue was dried in a high vacuum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04704464 |
| Source dataset | uspto-grants-1987_11 |
| ORD ID | ord-78935f969b6749c4b96021cbd113fd32 |
| Source note | uspto-grants-1987_11 |