Hydrochloric Acid → HCID 20163296, compound

Participants

Reaction Steps

A solution of 0.075 moles (2.85 g) lithium aluminum hydride in 150 ml absolute diethyl ether was put in a 250-ml 3-necked flask with a magnetic stirrer, high-power condenser, dropping funnel and internal thermometer. 0.2 moles (36 g) 1-(1,4,6-trimethylcyclohex-3-en-1-yl)propan-1-one (as per Example 4) was added dropwise to this solution with cooling. Then heating with refluxing was carried out for an hour, followed by cooling, and water was added to the reaction mixture until hydrogen evolution ended. Then enough 2N hydrochloric acid was added so that the precipitate formed could be dissolved. Lastly the phases were separated, the organic phase dried with sodium sulfate and the solvent drawn off. After fractional distillation via a 30-cm Vigreux column the desired end product was obtained in practically quantitative yield.

Provenance & Evidence