HRID24697

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID22571995

未命名化合物

结构：CCOC(=O)[C@H](Cc1ccc(OS(=O)(=O)C(F)(F)F)cc1)NC(=O)c1c(Cl)cccc1Cl

HCID54080286

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)[C@H](Cc1ccc(-c2c(OCOC)cccc2OCOC)cc1)NC(=O)c1c(Cl)cccc1Cl

HCID54573164

未命名化合物

PROCEDURE

实验过程

2,6-Di(methoxymethoxy)benzeneboronic acid (0.25 g) was coupled with N-(2,6-dichlorobenzoyl)-O-(trifluoromethanesulfonyl)-L-tyrosine ethyl ester in a similar procedure as described in Example 5-3) to afford N-(2,6-dichlorobenzoyl)-4-[2,6-di(methoxymethoxy)phenyl]-L-phenylalanine ethyl ester. ESMS: m/z 562 (MH+).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-399611d1bb7a456cbb4fdbdeec2e5319
来源数据集: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06855843B2
来源说明: uspto-grants-2005_02

反应 SMILES

[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][CH2:12][O:13][CH3:14])[C:6]=1B(O)O.[CH2:18]([O:20][C:21](=[O:49])[C@H:22]([CH2:34][C:35]1[CH:40]=[CH:39][C:38](OS(C(F)(F)F)(=O)=O)=[CH:37][CH:36]=1)[NH:23][C:24](=[O:33])[C:25]1[C:30]([Cl:31])=[CH:29][CH:28]=[CH:27][C:26]=1[Cl:32])[CH3:19]>>[CH2:18]([O:20][C:21](=[O:49])[C@H:22]([CH2:34][C:35]1[CH:40]=[CH:39][C:38]([C:6]2[C:5]([O:4][CH2:3][O:2][CH3:1])=[CH:10][CH:9]=[CH:8][C:7]=2[O:11][CH2:12][O:13][CH3:14])=[CH:37][CH:36]=1)[NH:23][C:24](=[O:33])[C:25]1[C:26]([Cl:32])=[CH:27][CH:28]=[CH:29][C:30]=1[Cl:31])[CH3:19]