Dichloromethane → HCID 20161047, compound

HRID 246987Notes

Reaction equation

HRID 246987 reaction equation
[C:1](Cl)([CH3:4])([CH3:3])[CH3:2].[CH3:6][CH:7]([CH2:10][CH2:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[CH2:8][Cl:9].[CH2:19](Cl)Cl>>[C:1]([C:16]1[CH:15]=[CH:14][C:13]([C:12]2[CH:11]=[CH:10][C:7]([CH3:6])=[C:8]([Cl:9])[CH:19]=2)=[CH:18][CH:17]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 10486tert-BUTYL CHLORIDEHCID 13577269HCID 13577269, compound

Product 1

HCID 20161047HCID 20161047, compound

Conditions

Temperature
50 °C

Procedure

27 g of tert.-butyl chloride are added dropwise to an ice-cooled mixture of 52 g of 2-methyl-5-phenylpentyl chloride and 4.9 g of FeCl3. The mixture is stirred for 7 hours at 50° C. and for 12 hours at room temperature, and taken up in methylene chloride, the solution is washed with water, dried over Na2SO4 and evaporated down, and the residue is distilled to give 40 g of 5-p-tert.-butylphenyl-2-methylphenyl chloride of boiling point 114°-118° C./0.2 mbar.

Workup

  1. temperaturecooled
  2. washthe solution is washed with water
  3. dry with materialdried over Na2SO4
  4. customevaporated down
  5. distillationthe residue is distilled

Sources & evidence

ORD record
ord-b5b5f4bc59604cb685c8068f09a9209c
Source dataset
uspto-grants-1987_11
Patent number
US04705553

Reaction notes

Loading…