HCID 20161185, compound → HCID 178486516, compound
Reaction equation
COC1C=C2C(=CC=1OC)CC(/C=C/C#N)=C2.[ClH:18].[OH:19][NH:20][C:21](=[NH:37])/[CH:22]=[CH:23]/[C:24]1[CH2:25][C:26]2[C:31]([CH:32]=1)=[CH:30][C:29]([O:33][CH3:34])=[C:28]([O:35][CH3:36])[CH:27]=2>>[ClH:18].[OH:19][NH:20][C:21](=[NH:37])[CH:22]=[CH:23][C:24]1[CH2:25][C:26]2[C:31]([CH:32]=1)=[CH:30][C:29]([O:33][CH3:34])=[C:28]([O:35][CH3:36])[CH:27]=2Participants
3
Procedure
Using the procedure described in Example 1 (E)-3-(5,6-dimethoxy-1H-indene-2-yl)-2-propenenitrile was converted into (E)-N-hydroxy-3-(5,6-dimethoxy-1H-indene-2-yl)-prop-2-ene-imidamide hydrochloride, m.p. 170° C. (dec.).
Sources & evidence
- ORD record
- ord-9a96087b986143ae9e4f327acab5d549
- Source dataset
- uspto-grants-1987_11
- Patent number
- US04705782
Reaction notes
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