HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → (3-Phenylbicyclo[2.2.2]oct-2-en-2-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 20161598 | HCID 20161598 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | (3-Phenylbicyclo[2.2.2]oct-2-en-2-yl)methanol | HCID 20161640 | — |
Reaction Steps
To lithium aluminium hydride (1 g; 0.03 m) in ether (50 ml) was added 3-formyl-2-phenylbicyclo[2,2,2]octane (4.2 g; 0.02 m) in ether (40 ml) dropwise at 0° C. After 1 hour, 5N sodium hydroxide (1 ml) followed by water (5 ml) was added cautiously. After filtering, the filtrate was evaporated to give an oil which was used directly in (e) below.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04705807 |
| Source dataset | uspto-grants-1987_11 |
| ORD ID | ord-ff5c61ebe03a4d6f9b61e4ed1aa7e9c3 |
| Source note | uspto-grants-1987_11 |