反应详情

12.5 g (45.7 mmoles) of acetoacetic acid N-[4-(6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)-phenyl]-amide in 225 ml of aqueous concentrated ammonia are heated under reflux for 2 hours. After cooling, the product if filtered off with suction and washed with water until it is neutral.

1. temperatureunder reflux for 2 hours
2. temperatureAfter cooling
3. filtrationthe product if filtered off with suction
4. washwashed with water until it