HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholinium 4-(3-methoxy-4-n-propoxyphenyl)-2-morpholino-4-oxobutyrate → 4-(4-Ethoxy-3-methoxyphenyl)-2-morpholino-4-oxobutyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholinium 4-(3-methoxy-4-n-propoxyphenyl)-2-morpholino-4-oxobutyrate | HCID 20160640 | — |
| Reactant | Morpholinium 4-(4-n-butoxy-3-methoxyphenyl)-2-morpholino-4-oxobutyrate | HCID 20160644 | — |
| Reactant | 4-(4-Allyloxy-3-methoxyphenyl)-2-morpholino-4-oxobutyric acid | HCID 20160650 | — |
| Reactant | Morpholinium 4-(4-ethoxy-3-methoxyphenyl)-2-morpholino-4-oxobutyrate | HCID 20160661 | — |
| Product | 4-(4-Ethoxy-3-methoxyphenyl)-2-morpholino-4-oxobutyric acid | HCID 20160643 | — |
Reaction Steps
In an analogous manner, morpholinium 4-(3-methoxy-4-n-propoxyphenyl)-2-morpholino-4-oxobutyrate, m.p. 110°; morpholinium 4-(4-n-butoxy-3-methoxyphenyl)-2-morpholino-4-oxobutyrate, m.p. 120°; 4-(4-allyloxy-3-methoxyphenyl)-2-morpholino-4-oxobutyric acid, m.p. 166°; morpholinium 4-(4-ethoxy-3-methoxyphenyl)-2-morpholino-4-oxobutyrate, m.p. 131°; 4-(4-ethoxy-3-methoxyphenyl)-2-morpholino-4-oxobutyric acid, m.p. 157° are prepared from the corresponding acetophenones.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04707481 |
| Source dataset | uspto-grants-1987_11 |
| ORD ID | ord-c0621a9a2f29438ba20347717bc74c80 |
| Source note | uspto-grants-1987_11 |