HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 53435299, compound → 3,5-Difluoro-4-methoxybenzenepropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 53435299 | HCID 53435299 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3,5-Difluoro-4-methoxybenzenepropanoic acid | HCID 14049930 | — |
Reaction Steps
A solution of 3-(3,5-difluoro-4-methoxyphenyl)propenoic acid (0.078 mol) in tetrahydrofuran (100 ml) and a slurry of 10% palladium on carbon (2 g) in ethyl acetate were reacted substantially as described in Example 7C above to obtain 16.7 g (99%), white crystals: mp 72°-73°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04707488 |
| Source dataset | uspto-grants-1987_11 |
| ORD ID | ord-1fcc2cd938814f659ef0dd944b372ad2 |
| Source note | uspto-grants-1987_11 |