反应详情

23.6 g of 3-(4,4-diphenylpiperid-1-yl)-propanol are dissolved in 100 ml of absolute toluene, and 16 ml of a 50% strength solution of diketene in acetone are added, with stirring. After the mixture has been left to stand at room temperature for several days (control by thin layer chromatography), it is concentrated, and the residue is dried under a high vacuum. The pale yellow viscous oil which remains is employed for the next stage without further purification.

1. waitAfter the mixture has been left
2. waitto stand at room temperature for several days
3. concentration(control by thin layer chromatography), it is concentrated
4. customthe residue is dried under a high vacuum
5. customThe pale yellow viscous oil which remains is employed for the next stage without further purification