HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → (4-Bromo-3-methoxyphenyl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Borane | HCID 6331 | — |
| Reactant | 4-Bromo-3-methoxybenzoic acid | HCID 16215867 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | (4-Bromo-3-methoxyphenyl)methanol | HCID 13551345 | — |
Reaction Steps
4-Bromo-3-methoxybenzoic acid (23.1 g, 0.1 m) dissolved in tetrahydrofuran (200 ml) is added to 1M borane in tetrahydrofuran (150 ml) stirred at 5°. The mixture is refluxed, cooled, treated with methanol, refluxed and concentrated in vacuo to give 4-bromo-3-methoxybenzyl alcohol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04707483 |
| Source dataset | uspto-grants-1987_11 |
| ORD ID | ord-d29644f06690430f91044127a92bcee1 |
| Source note | uspto-grants-1987_11 |