HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 20160668, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (4-Bromo-3-methoxyphenyl)-methanol | HCID 13551345 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 20160668 | HCID 20160668 | — |
Reaction Steps
4-Bromo-3-methoxybenzyl alcohol (21.7 g, 0.1 m) dissolved in toluene (200 ml) containing pyridine (11.8 g, 0.15 m) is stirred at 5° and treated wiih thionyl chloride (23.8 g, 0.2 m). The mixture is stirred, diluted with water and the organic layer washed with dilute hydrochloric acid, dried and concentrated in vacuo to give 4-bromo-3-methoxybenzyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04707483 |
| Source dataset | uspto-grants-1987_11 |
| ORD ID | ord-2b5d87918c484b3b8c5eb1f62f3d0379 |
| Source note | uspto-grants-1987_11 |