HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 5-bromovalerate → HCID 13911280, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 5-bromovalerate | HCID 84580 | — |
| Reactant | 3-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]thieno[3,2-d]pyrimidine-2,4-dione | HCID 13911278 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 13911280 | HCID 13911280 | 82% |
Reaction Steps
The title compound was produced following the procedure of Example 13 using dimethylformamide as solvent, the thienopyrimidine-2,4-dione (3.0 g, 7.76 mmol) from Example 19, and ethyl 5-bromovalerate was used as the alkylating agent. The title compound was isolated in 82% yield (3.3 g), after recrystallization from EtOH, mp 118°-119° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04707550 |
| Source dataset | uspto-grants-1987_11 |
| ORD ID | ord-0a6f3c605bdf46849cc42abc5a5c009f |
| Source note | uspto-grants-1987_11 |