Acetic Anhydride → 1H-Indole, 1-acetyl-3-(4-methoxybenzoyl)-

Participants

Reaction Steps

1 g of compound 1 was added to the mixture of 50 ml each of acetic anhydride and pyridine, and then the solution was stirred overnight at room temperature. The reaction mixture was evaporated to dryness under reduced pressure. The resulting crude crystals were recrystallized from chloroform to obtain 3-(p-methoxybenzoyl)-N-acetylindole (compound 5) in the form of white crystals. (Yield: 90%).

Provenance & Evidence