Sodium Hydroxide → HCID 178484748, compound

HRID 24756Notes

Reaction equation

HRID 24756 reaction equation
C([O:3][C:4]([CH2:6][N:7]([CH3:34])[C:8]([C:10]1[CH:11]=[C:12]([NH:16]/[C:17](=[C:24]2\[C:25](=[O:33])[NH:26][C:27]3[C:32]\2=[CH:31][CH:30]=[CH:29][CH:28]=3)/[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:13]=[CH:14][CH:15]=1)=[O:9])=[O:5])C.[OH-].[Na+]>C(O)C>[C:4]([CH2:6][N:7]([CH3:34])[C:8]([C:10]1[CH:11]=[C:12]([NH:16]/[C:17](=[C:24]2\[C:25](=[O:33])[NH:26][C:27]3[C:32]\2=[CH:31][CH:30]=[CH:29][CH:28]=3)/[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:13]=[CH:14][CH:15]=1)=[O:9])([OH:5])=[O:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178472721HCID 178472721, compound

Product 1

HCID 178484748HCID 178484748, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 8 from (Z)-3-{1-[3-(N-ethoxycarbonylmethyl-N-methylaminocarbonyl)-phenylamino]-1-phenyl-methylidene}-2-indolinone and sodium hydroxide solution in ethanol.

Sources & evidence

ORD record
ord-030e51302b45452085d9f25adfda74a9
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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