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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24757Generated: October 26, 2026

Sodium Hydroxide → HCID 178452787, compound

https://huagongshe.com/reaction/24757

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactanttert-Butyl (4-aminophenyl)carbamateHCID 688611—
Reactant1-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinoneHCID 54237888—
SolventMethanolHCID 887—
SolventDimethylformamideHCID 6228—
ProductHCID 178452787HCID 178452787—

Reaction Steps

Prepared analogously to Example 1 from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone and 4-tert.butoxycarbonylamino-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855710B2
Source datasetuspto-grants-2005_02
ORD IDord-cd0cdd354bb6496d88cd8599ea2fcba1
Source noteuspto-grants-2005_02