2,4,5-Trimethylimidazole → 1,3-Dihydro-4-methyl-5-[4-(2,4,5-trimethyl-1H-imidazol-1-yl)benzoyl]-2H-imidazol-2-one
Reaction equation
F[C:2]1[CH:16]=[CH:15][C:5]([C:6]([C:8]2[NH:9][C:10](=[O:14])[NH:11][C:12]=2[CH3:13])=[O:7])=[CH:4][CH:3]=1.[CH3:17][C:18]1[NH:19][C:20]([CH3:24])=[C:21]([CH3:23])[N:22]=1>>[CH3:13][C:12]1[NH:11][C:10](=[O:14])[NH:9][C:8]=1[C:6](=[O:7])[C:5]1[CH:15]=[CH:16][C:2]([N:19]2[C:20]([CH3:24])=[C:21]([CH3:23])[N:22]=[C:18]2[CH3:17])=[CH:3][CH:4]=1Participants
3
Procedure
In a manner similar to Example IV react 4-(4-fluorobenzoyl)-1,3-dihydro-5-methyl-2H-imidazol-2-one with 2,4,5-trimethyl-1H-imidazole to produce the title compound.
Sources & evidence
- ORD record
- ord-9d34eaff7f0546e380d0f0714841c11c
- Source dataset
- uspto-grants-1987_11
- Patent number
- US04709043
Reaction notes
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