HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-tert-Butyl-6-methylphenol → 3-(3-Tert-butyl-4-hydroxy-5-methylphenyl)-1-n-dodecylpyrrolidine-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-tert-Butyl-6-methylphenol | HCID 16678 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1H-Pyrrole-2,5-dione, 1-dodecyl- | HCID 87191 | — |
| Solvent | tert-Butanol | HCID 6386 | — |
| Product | 3-(3-Tert-butyl-4-hydroxy-5-methylphenyl)-1-n-dodecylpyrrolidine-2,5-dione | HCID 14148377 | — |
Reaction Steps
This compound is prepared by the procedure of Example 1 from 1.20 g (50 mmol) of sodium hydride, 8.21 g (50 mmol) of 2-tert-butyl-6-methylphenol, and 13.27 g (50 mmol) of N-n-dodecylmaleimide in tert-butyl alcohol. The residue is purified by preparative HPLC (8:2 heptane:ethyl acetate eluent) to give 4.70 g (22%) of a yellow wax.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04709050 |
| Source dataset | uspto-grants-1987_11 |
| ORD ID | ord-f454d7b30ea141779d1e7812070e00b0 |
| Source note | uspto-grants-1987_11 |