Hydrogen chloride-ethyl acetate → HCID 178479238, compound

HRID 24764Notes

Reaction equation

HRID 24764 reaction equation
C(OC([NH:8][CH2:9][C:10]([NH:12][C:13]1[CH:18]=[CH:17][C:16]([NH:19]/[C:20](=[C:27]2\[C:28](=[O:36])[NH:29][C:30]3[C:35]\2=[CH:34][CH:33]=[CH:32][CH:31]=3)/[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[CH:15][CH:14]=1)=[O:11])=O)(C)(C)C.C(OCC)(=O)C.[ClH:43]>ClCCl>[ClH:43].[NH2:8][CH2:9][C:10]([NH:12][C:13]1[CH:14]=[CH:15][C:16]([NH:19]/[C:20](=[C:27]2\[C:28](=[O:36])[NH:29][C:30]3[C:35]\2=[CH:34][CH:33]=[CH:32][CH:31]=3)/[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[CH:17][CH:18]=1)=[O:11]

Participants

4

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 178453805HCID 178453805, compound

Product 1

HCID 178479238HCID 178479238, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared analogously to Example 29a from (Z)-3-[1-(4-tert.butoxycarbonylaminomethylcarbonylamino-phenylamino)-1-phenyl-methylidene]-2-indolinone and ethyl acetate/hydrogen chloride in dichloromethane.

Sources & evidence

ORD record
ord-8c1a0f763e134725a382272c6c9a4fdb
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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