Sodium Hydroxide → HCID 178482163, compound

HRID 24766Notes

Reaction equation

HRID 24766 reaction equation
FC(F)(F)[C:3]([N:5]([C:7]1[CH:8]=[C:9]([NH:13]/[C:14](=[C:21]2\[C:22](=[O:30])[NH:23][C:24]3[C:29]\2=[CH:28][CH:27]=[CH:26][CH:25]=3)/[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:10]=[CH:11][CH:12]=1)C)=O.[OH-].[Na+]>CO>[CH3:3][NH:5][C:7]1[CH:8]=[C:9]([NH:13]/[C:14](=[C:21]2\[C:22](=[O:30])[NH:23][C:24]3[C:29]\2=[CH:28][CH:27]=[CH:26][CH:25]=3)/[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:10]=[CH:11][CH:12]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178485730HCID 178485730, compound

Product 1

HCID 178482163HCID 178482163, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Prepared analogously to Example 8 from (Z)-3-{1-[3-(N-trifluoroacetyl-N-methyl-amino)-phenylamino]-1-phenyl-methylidene}-2-indolinone and sodium hydroxide solution in methanol.

Sources & evidence

ORD record
ord-7a74f64692884c1a99544bc43126e689
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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