Hydrogen chloride-ethyl acetate → HCID 178479241, compound

HRID 24783Notes

Reaction equation

HRID 24783 reaction equation
C(OC([NH:8][CH2:9][C:10]([NH:12][CH2:13][C:14]1[CH:19]=[CH:18][C:17]([NH:20]/[C:21](=[C:28]2\[C:29](=[O:37])[NH:30][C:31]3[C:36]\2=[CH:35][CH:34]=[CH:33][CH:32]=3)/[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:16][CH:15]=1)=[O:11])=O)(C)(C)C.C(OCC)(=O)C.[ClH:44]>ClCCl>[ClH:44].[NH2:8][CH2:9][C:10]([NH:12][CH2:13][C:14]1[CH:15]=[CH:16][C:17]([NH:20]/[C:21](=[C:28]2\[C:29](=[O:37])[NH:30][C:31]3[C:36]\2=[CH:35][CH:34]=[CH:33][CH:32]=3)/[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:18][CH:19]=1)=[O:11]

Participants

4

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 178453822HCID 178453822, compound

Product 1

HCID 178479241HCID 178479241, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared analogously to Example 29a from (Z)-3-[1-(4-tert.butoxycarbonylaminomethylcarbonylaminomethyl-phenylamino)-1-phenyl-methylidene]-2-indolinone and ethyl acetate/hydrogen chloride in dichloromethane.

Sources & evidence

ORD record
ord-debc1ecde35e4dcfa061456f67870758
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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