HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroethane → N-Methyl-N-{[1-[3-(p-fluorophenoxy)propyl]-4-piperidyl]methyl}-5-isoquinolinesulfonamide dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroethane | HCID 6337 | — |
| Reactant | N-Methyl-N-{[1-[3-(p-fluorophenoxy)propyl]-4-piperidyl]methyl}-5-isoquinolinesulfonamide | HCID 9890945 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N-Methyl-N-{[1-[3-(p-fluorophenoxy)propyl]-4-piperidyl]methyl}-5-isoquinolinesulfonamide dihydrochloride | HCID 19764599 | — |
Reaction Steps
5.5 g of the compound obtained in stage A is taken up in 10 cm3 of acetonitrile. 7.5 cm3 of a 3.3N solution of hydrochloric ether are added to this solution. 3.1 g of a solid which corresponds to the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05208243 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-5e7f19ff56af4ccabb05d3f49423a133 |
| Source note | uspto-grants-1993_05 |