HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-4-hydroxybenzaldehyde → 5-[(3-Bromo-4-hydroxyphenyl)methylene]-2-thioxo-4-imidazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-4-hydroxybenzaldehyde | HCID 76308 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 2-Thiohydantoin | HCID 1274030 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5-[(3-Bromo-4-hydroxyphenyl)methylene]-2-thioxo-4-imidazolidinone | HCID 3873910 | 75.8% |
Reaction Steps
Prepared according to the procedure described in Example 1 using 3-bromo-4-hydroxybenzaldehyde (3.1 g, 15 mmoles), 2-thiohydantoin (1.7 g, 15 mmoles), sodium acetate (4.5 g, 55 mmoles), and acetic acid (35 ml), to afford the pure product (3.4 g), mp 262° C. (dec).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05208250 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-d8a5fba2efb349b8b653a4192d4719a7 |
| Source note | uspto-grants-1993_05 |