tert-Butyldimethylsilyl chloride → HCID 54532766, compound

HRID 247892Notes

Reaction equation

HRID 247892 reaction equation
[OH:1][C:2]1[C:7]([O:8][CH3:9])=[CH:6][C:5]([CH:10]=[CH:11][C:12](=[O:17])[CH2:13][C:14](=[O:16])[CH3:15])=[CH:4][C:3]=1[O:18][CH3:19].[C:20]([Si:24](Cl)([CH3:26])[CH3:25])([CH3:23])([CH3:22])[CH3:21]>>[Si:24]([O:1][C:2]1[C:3]([O:18][CH3:19])=[CH:4][C:5]([CH:10]=[CH:11][C:12](=[O:17])[CH2:13][C:14](=[O:16])[CH3:15])=[CH:6][C:7]=1[O:8][CH3:9])([C:20]([CH3:23])([CH3:22])[CH3:21])([CH3:26])[CH3:25]

Participants

3

Reactant 2

HCID 28928tert-Butyldimethylsilyl chlorideHCID 54313035HCID 54313035, compound

Product 1

HCID 54532766HCID 54532766, compound

Procedure

According to the procedure of Example 22C, 1-(4'-hydroxy-3',5'-dimethoxyphenyl)-1-hexene-3,5-dione is reacted with t-butylchlorodimethyl silane to afford 1-(4'-t-butyldimethylsilyloxy-3',5'-dimethoxyphenyl)-1-hexene-3,5-dione suitably pure for further use.

Sources & evidence

ORD record
ord-cf936f2f69cc4fdf8ae2f86b3a658ae6
Source dataset
uspto-grants-1993_05
Patent number
US05208251

Reaction notes

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