反应详情

温度

115 °C

A mixture of 0.808 g of product from Example 5 and 5.39 ml of methyl iodide is heated, in a sealed dark tube, at 115° C. for 23 hours. The cooled reaction mixture is concentrated in vacuo and the residue purified by column chromatography (silica gel: 20% methyl alcohol/chloroform) to give 0.63 g of the desired product as cream crystals.

1. customThe cooled reaction mixture
2. concentrationis concentrated in vacuo
3. customthe residue purified by column chromatography (silica gel: 20% methyl alcohol/chloroform)