Methyl iodide → 2-[[Acetyl[3-(1,1-dimethylethyl)-4-(tetradecyloxy)-benzoyl]amino]methyl]-1-methylpyridinium iodide

HRID 247944Notes

Reaction equation

HRID 247944 reaction equation
[C:1]([N:4]([CH2:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][N:34]=1)[C:5](=[O:31])[C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])=[C:8]([C:27]([CH3:30])([CH3:29])[CH3:28])[CH:7]=1)(=[O:3])[CH3:2].[CH3:39][I:40]>>[I-:40].[C:1]([N:4]([CH2:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][N+:34]=1[CH3:39])[C:5](=[O:31])[C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])=[C:8]([C:27]([CH3:28])([CH3:29])[CH3:30])[CH:7]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 10075454N-Acetyl-3-(1,1-Dimethylethyl)-4-(tetradecyloxy)-N-(2-pyridinylmethyl)benzamide

Product 1

HCID 99395852-[[Acetyl[3-(1,1-dimethylethyl)-4-(tetradecyloxy)-benzoyl]amino]methyl]-1-methylpyridinium iodide

Procedure

The title compound is prepared by the procedure of Example 28 using 0.256 g of product from Example 34 and 1.52 ml of methyl iodide. The residue is recrystallized from methyl alcohol to give 0.315 g of the desired product as yellow crystals.

Workup

  1. customThe residue is recrystallized from methyl alcohol

Sources & evidence

ORD record
ord-c48e0016b00a4d24b2b354d622f680ae
Source dataset
uspto-grants-1993_05
Patent number
US05208247

Reaction notes

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