反应详情

17.5 g (0.10 mol) of 1-acetyl-2-indolinone are dissolved in 100 ml of conc. sulphuric acid and at −10° C. 8.8 g (0.11 mol) of ammonium nitrate are added batchwise and stirred for 15 minutes. The reaction is poured onto ice water, suction filtered and washed with water. The residue is distributed in ethyl acetate/water, the combined organic extracts are dried and concentrated by evaporation.

1. additionThe reaction is poured onto ice water, suction
2. filtrationfiltered
3. washwashed with water
4. customthe combined organic extracts are dried
5. concentrationconcentrated by evaporation