Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Myristyl bromide → [4-(Tetradecyloxy)phenyl]acetic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Myristyl bromide | HCID 8208 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Benzeneacetic acid, 4-hydroxy-, methyl ester | HCID 518900 | — |
| 촉매 | Potassium Iodide | HCID 4875 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | [4-(Tetradecyloxy)phenyl]acetic acid methyl ester | HCID 10316608 | 63.3% |
반응 단계
A mixture of 200 g of methyl 4-hydroxyphenylacetate, 350.4 g of 1-bromotetradecane, 207.9 g of potassium carbonate, 10 g of potassium iodide and 1.5 L of acetone is heated at reflux temperature for 24 hours. The reaction is cooled to room temperature, concentrated in vacuo and the residue is recrystallized from cold hexane to give 276.0 g of the desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05208247 |
| 출처 데이터셋 | uspto-grants-1993_05 |
| ORD ID | ord-b5c5404327bd4c32abb4ab6dc6a6df55 |
| 출처 메모 | uspto-grants-1993_05 |