反应详情

The title compound is prepared by the procedure of Example 64 using 60 g of product from Example 66, 24.84 g of potassium hydroxide, 45 ml of water and 650 ml of ethyl alcohol. The reaction is heated at reflux temperature for 41 hours. The residue is recrystallized from methylene chloride/hexane to give 38 g of the desired product as cream needles.

1. temperatureThe reaction is heated
2. temperatureat reflux temperature for 41 hours
3. customThe residue is recrystallized from methylene chloride/hexane