Methyl iodide → HCID 9985927, compound

HRID 247984Notes

Reaction equation

HRID 247984 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][N:8]([CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[O:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[C:9](=[O:11])[CH3:10].[CH3:34][I:35]>>[I-:35].[C:9]([N:8]([CH2:7][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][N+:1]=1[CH3:34])[CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[O:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])(=[O:11])[CH3:10]

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 10004024HCID 10004024, compound

Product 1

HCID 9985927HCID 9985927, compound

Procedure

The title compound is prepared by the procedure of Example 28 using 0.90 g of product from Example 75 and 6.19 ml of methyl iodide. The residue is purified by crystallization from methyl alcohol to give 1.135 g of the desired product as yellow crystals. The spectral data indicates the presence of 2 rotomers.

Workup

  1. customThe residue is purified by crystallization from methyl alcohol

Sources & evidence

ORD record
ord-5737e1178e4d4f85a19b20492dee0184
Source dataset
uspto-grants-1993_05
Patent number
US05208247

Reaction notes

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