HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrophenol → 4-Nitrophenyl tetradecyl ether
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrophenol | HCID 980 | — |
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Myristyl bromide | HCID 8208 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Catalyst | Trioctylmethylammonium chloride | HCID 21218 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-Nitrophenyl tetradecyl ether | HCID 10337051 | — |
Reaction Steps
A mixture of 75 g of 4-nitrophenol, 149.5 g of 1-bromotetradecane, 26.96 g of sodium hydroxide, 2.18 g of trioctyl methylammonium chloride, 400 ml of toluene and 400 of water is heated at reflux for 65 hours. The organic layer is separated, washed with 1N sodium hydroxide and dilute hydrochloric acid, dried and concentrated in vacuo. The residue is recrystallized from petroleum ether to give the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05208247 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-a4c6f5b05695488490e9ebe1e9f8dbc1 |
| Source note | uspto-grants-1993_05 |