HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 248024Generated: October 26, 2026
Methyl iodide → 1-Methyl-2-[[(methylsulfonyl)[[4-(tetradecyloxy)phenyl]methyl]amino]methyl]pyridinium iodide
https://huagongshe.com/reaction/248024
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | N-(2-Pyridinylmethyl)-N-[[4-(tetradecyloxy)phenyl]methyl]methanesulfonamide | HCID 19014986 | — |
| Product | 1-Methyl-2-[[(methylsulfonyl)[[4-(tetradecyloxy)phenyl]methyl]amino]methyl]pyridinium iodide | HCID 19015610 | 99.6% |
Reaction Steps
A mixture of 0.350 g of product from Example 122 and 5.08 g of methyl iodide is heated at 90° C. for 17 hours. Thin layer chromatography shows the presence of starting material. The mixture is reheated at 125° C. for 23 hours. The reaction is concentrated in vacuo to give 0.45 g of the desired product as pale yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05208247 |
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| Source dataset | uspto-grants-1993_05 |
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| ORD ID | ord-9f01f58637f44ec4a4c62a4f5ef6c238 |
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| Source note | uspto-grants-1993_05 |
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