Methyl iodide → HCID 19016445, compound

HRID 248042Notes

Reaction equation

HRID 248042 reaction equation
[C:1]1([N:7]([CH2:16][C:17]2[CH:22]=[CH:21][C:20]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])=[CH:19][CH:18]=2)[C:8]([C:10]2[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=2)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:38][I:39]>>[I-:39].[CH3:38][N+:12]1[CH:13]=[CH:14][CH:15]=[C:10]([C:8]([N:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH2:16][C:17]2[CH:18]=[CH:19][C:20]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])=[CH:21][CH:22]=2)=[O:9])[CH:11]=1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 19015330HCID 19015330, compound

Product 1

HCID 19016445HCID 19016445, compoundYield 99.3%

Conditions

Temperature
100 °C

Procedure

A mixture of 0.80 g of product from Example 146 and 11.34 g of methyl iodide is heated, in a sealed tube, at 100° C. for 10 hours. The reaction is concentrated in vacuo to give 1.02 g of the desired product as light yellow crystals.

Workup

  1. concentrationThe reaction is concentrated in vacuo

Sources & evidence

ORD record
ord-a3163fb398444345b3d58b7bf7d33439
Source dataset
uspto-grants-1993_05
Patent number
US05208247

Reaction notes

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