HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 1-(Bromomethyl)-2-chloro-4-iodobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 2-Chloro-4-iodotoluene | HCID 2801329 | — |
| Catalyst | Benzoyl Peroxide | HCID 7187 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 1-(Bromomethyl)-2-chloro-4-iodobenzene | HCID 22058683 | 93.1% |
Reaction Steps
A mixture of 3-chloro-4-methyliodobenzene (9.0 g), N-bromosuccinimide (8.5 g), benzoyl peroxide (0.3 g) and carbon tetrachloride (80 ml) was stirred and heated to reflux for 3 hours. The mixture was cooled to ambient temperature and filtered. The filtrate was evaporated to give 4-bromomethyl-3-chloroiodobenzene (11 g) which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05208259 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-935f0674609840a5b887ec8d5a6be8ee |
| Source note | uspto-grants-1993_05 |