Hydrogen chloride-ethyl acetate → HCID 178507734, compound

HRID 24810Notes

Reaction equation

HRID 24810 reaction equation
C(OC([NH:8][C:9]1[CH:14]=[CH:13][C:12]([NH:15]/[C:16](=[C:23]2\[C:24](=[O:35])[NH:25][C:26]3[C:31]\2=[CH:30][C:29]([N+:32]([O-:34])=[O:33])=[CH:28][CH:27]=3)/[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:11][CH:10]=1)=O)(C)(C)C.C(OCC)(=O)C.Cl>ClCCl>[NH2:8][C:9]1[CH:14]=[CH:13][C:12]([NH:15]/[C:16](=[C:23]2\[C:24](=[O:35])[NH:25][C:26]3[C:31]\2=[CH:30][C:29]([N+:32]([O-:34])=[O:33])=[CH:28][CH:27]=3)/[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)=[CH:11][CH:10]=1

Participants

4

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 178452788HCID 178452788, compound

Product 1

HCID 178507734HCID 178507734, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared analogously to Example 29a from (Z)-3-[1-(4-tert.butoxycarbonylamino-phenylamino)-1-phenyl-methylidene]-5-nitro-2-indolinone and ethyl acetate/hydrogen chloride in dichloromethane.

Sources & evidence

ORD record
ord-f968bb299f084ee3b152e0d17f0c9920
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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