HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cetyl Alcohol → Ethyl 2-[(hexadecyloxy)methyl]-2-propenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cetyl Alcohol | HCID 2682 | — |
| Reactant | 2-Dimethylaminopyridine | HCID 21885 | — |
| Reactant | Ethyl 2-(acetoxymethyl)acrylate | HCID 10997496 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Ethyl 2-[(hexadecyloxy)methyl]-2-propenoate | HCID 12971817 | 39.3% |
Reaction Steps
To a mixture of 1.1 g of 1-hexadecanol and 400 mg of 2-[(acetyloxy)methyl]-2-propenoic acid, ethyl ester in 15 ml of dichloromethane is added 550 mg of dimethylaminopyridine. This mixture is stirred overnight, then the solvent is evaporated and the residue subjected to preparative tlc (25% ethyl acetate/petroleum ether), to give 324 mg of the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05208223 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-a68765fbb5c5487ea982e6d8ac4db2f2 |
| Source note | uspto-grants-1993_05 |