HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → 3-(Hexadecylthio)-1-propanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Lithium borohydride | HCID 4148881 | — |
| Reactant | Ethyl 3-(hexadecylthio)propanoate | HCID 19764352 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-(Hexadecylthio)-1-propanol | HCID 17831703 | 99.1% |
Reaction Steps
To a slurry of 147.4 mg of lithium borohydride in ml of tetrahydrofuran is added 2.4 g of 3-(hexadecylthio)propanoic acid, ethyl ester. This mixture is refluxed overnight, poured into water and extracted with ethyl acetate, to give 2.1 g of the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05208223 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-4d31af5dd4444ba083c369ff0c102fa7 |
| Source note | uspto-grants-1993_05 |