Sodium Sulfate → HCID 19764335, compound

HRID 248157Notes

Reaction equation

HRID 248157 reaction equation
[H-].[Al+3].[Li+].[H-].[H-].[H-].[N:7]([CH2:10][CH:11]([CH2:21][O:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[CH2:12][O:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[N+]=[N-].S([O-])([O-])(=O)=O.[Na+].[Na+]>CCOCC>[CH2:23]([O:22][CH2:21][CH:11]([CH2:12][O:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[CH2:10][NH2:7])[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38]

Participants

5

Reactant 3

HCID 24436Sodium SulfateHCID 19764416HCID 19764416, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 19764335HCID 19764335, compoundYield 99.9%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Conditions

Temperature
0 °C

Procedure

To a solution of 0.87 g of lithium aluminum hydride in 80 ml of ether under argon is added, with stirring, over 30 minutes, a solution of 8.5 g of [[3- azido-2-[(hexadecyloxy)methyl]propoxy]methyl]benzene in 80 ml of ether. This mixture is refluxed for 3 hours, then cooled to 0° C. and 8 ml of saturated aqueous sodium sulfate solution is added. The mixture is filtered and the filtrate evaporated, to give 8.0 g of the desired compound as an oil.

Workup

  1. temperatureThis mixture is refluxed for 3 hours
  2. filtrationThe mixture is filtered
  3. customthe filtrate evaporated

Sources & evidence

ORD record
ord-352a653c21144360bd3be04c011dee06
Source dataset
uspto-grants-1993_05
Patent number
US05208223

Reaction notes

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