HuagongsheHuagongshe Chemistry Print Report · For research reference only
Desmethylnaproxen → alpha-Methyl-6-[(2-phenyl-4-thiazolyl)methoxy]-2-naphthaleneacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Desmethylnaproxen | HCID 162920 | — |
| Reactant | 4-(Chloromethyl)-2-phenyl-1,3-thiazole | HCID 236969 | — |
| Product | alpha-Methyl-6-[(2-phenyl-4-thiazolyl)methoxy]-2-naphthaleneacetic acid | HCID 15030188 | — |
Reaction Steps
The title compound is prepared according to the method of Example 7 using 2-phenyl-4-(chloromethyl)thiazole and racemic 6-hydroxy-α-methyl-2-naphthaleneacetic acid. White crystals are obtained having a melting point of 163°-164° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05208344 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-16924eae082040dfa40f50968e53f5ae |
| Source note | uspto-grants-1993_05 |