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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24818Generated: October 26, 2026

Sodium Hydroxide → HCID 178480922, compound

https://huagongshe.com/reaction/24818

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantN-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamideHCID 21927707—
Reactant1-Acetyl-3-{1-ethoxy-1-phenylmethylidene}-5-nitro-2-indolinoneHCID 54280104—
SolventMethanolHCID 887—
SolventDimethylformamideHCID 6228—
ProductHCID 178480922HCID 178480922—

Reaction Steps

Prepared analogously to Example 82 from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-5-nitro-2-indolinone and 4-[N—(N-methylpiperazinomethylcarbonyl)-N-methyl-amino]-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855710B2
Source datasetuspto-grants-2005_02
ORD IDord-de6103e3f9ae4d69b00d1aa8b0d18b7a
Source noteuspto-grants-2005_02