Sodium hydride → HCID 178447979, compound

Participants

Reaction Steps

A mixture of 0.2 mol of (trans-4-propylcyclohexylmethyl)triphenylphosphonium bromide (prepared from trans-4-propylcyclohexylmethyl bromide and triphenylphosphine) and 150 ml of DMSO gives (sic) at 0° C. to a mixture of 0.2 mol of sodium hydride and 100 ml of DMSO. After the mixture has been stirred at room temperature for 10 minutes, a mixture of 0.2 mol of trans-4-trifluoromethyl-1-formyulcyclohexane (prepared as in Example 3) and 50 ml of DMSO is added dropwise. The mixture is warmed for 1 hour at 65° C. and subjected to customary work-up. The product is obtained as a colourless dye (sic).

Provenance & Evidence