HCID 178447979, compound → HCID 178447980, compound

HRID 248308Notes

Reaction equation

HRID 248308 reaction equation
[CH2:1]([C@H:4]1[CH2:9][CH2:8][C@H:7]([CH:10]=[CH:11][C@H:12]2[CH2:17][CH2:16][C@H:15]([C:18]([F:21])([F:20])[F:19])[CH2:14][CH2:13]2)[CH2:6][CH2:5]1)[CH2:2][CH3:3]>[Pd].CO>[CH2:1]([C@H:4]1[CH2:5][CH2:6][C@H:7]([CH2:10][CH2:11][C@H:12]2[CH2:13][CH2:14][C@H:15]([C:18]([F:19])([F:20])[F:21])[CH2:16][CH2:17]2)[CH2:8][CH2:9]1)[CH2:2][CH3:3]

Participants

4

Reactant 1

HCID 178447979HCID 178447979, compound

Product 1

HCID 178447980HCID 178447980, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of 0.1 mol of 1-(trans-4-propylcyclohexyl)-2-(trans-4-trifluoromethylcyclohexyl)ethene, 200 ml of methanol and 5 g of palladium/activated charcoal (15%) is hydrogenated for 2 hours under a pressure of 2 bar and at a temperature of 50° C. Customary work-up gives the product as a colourless solid.

Sources & evidence

ORD record
ord-c76ec27a3e0645b89306beb987ce2923
Source dataset
uspto-grants-1993_05
Patent number
US05209868

Reaction notes

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