Toluene → HCID 178444382, compound

HRID 248311Notes

Reaction equation

HRID 248311 reaction equation
[F:1][C:2]([F:12])([F:11])[C@H:3]1[CH2:8][CH2:7][C@H:6]([CH:9]=[O:10])[CH2:5][CH2:4]1.[CH2:13]([C@H:18]1[CH2:23][CH2:22][C@H:21]([CH:24]([CH3:28])[CH:25](O)[OH:26])[CH2:20][CH2:19]1)[CH2:14][CH2:15][CH2:16][CH3:17].C1(C)C=CC=CC=1>O>[F:1][C:2]([F:11])([F:12])[C@H:3]1[CH2:4][CH2:5][C@H:6]([CH:9]2[O:26][CH2:25][CH:24]([C@H:21]3[CH2:20][CH2:19][C@H:18]([CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[CH2:23][CH2:22]3)[CH2:28][O:10]2)[CH2:7][CH2:8]1

Participants

5

Reactant 3

HCID 1140TolueneHCID 178444477HCID 178444477, compoundHCID 178520943HCID 178520943, compound

Product 1

HCID 178444382HCID 178444382, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 0.02 mol of tras-4-trifluoromethyl-1-formylcyclohexane (prepared as in Example 3), 0.02 mol of 2-(trans-4-pentylcyclohexyl)propanediol (prepared as in DE 3,227,916), 30 ml of toluene and 0.5 g of pTSOH is heated for 6 hours on a water separator. The product is obtained after customary work-up and crystallization.

Workup

  1. customThe product is obtained
  2. customafter customary work-up and crystallization

Sources & evidence

ORD record
ord-0e9e2334908a4d8787a7eaa1f548c654
Source dataset
uspto-grants-1993_05
Patent number
US05209868

Reaction notes

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