Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Chlorotrimethylsilane | HCID 6397 | — |
| Reactant | 1,5-Diazabicyclo(5,4,0)undec-5-ene | HCID 314112 | — |
| Reactant | Methyl (E)-4-oxo-6-phenyl-5-hexenoate | HCID 11127729 | — |
| Product | HCID 86746829 | HCID 86746829 | — |
Reaction Steps
3 g of the product of Step B , 45 ml of diethyl ether and 2.2 ml of trimethylchlorosilane were mixed together and after the mixture was cooled to 0° C., then 2.5 ml of 1,5-diaza-5-bicyclo-[5,4,0]-undecene (DBU) and 20 ml of diethyl ether were added. The mixture was stirred while allowing the temperature to rise to 20° to 21° C. for one hour. After filtration, the ether was evaporated off to obtain 4.2 g of the desired product which was used as is in the following step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05210093 |
|---|
| Source dataset | uspto-grants-1993_05 |
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| ORD ID | ord-79d28e346a9643198b0f6d7c0a86f992 |
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| Source note | uspto-grants-1993_05 |
|---|
