Hydrogen chloride-ethyl acetate → HCID 178482860, compound

HRID 24835Notes

Reaction equation

HRID 24835 reaction equation
C(O[C:6]([N:8]([CH2:10][C:11]1[CH:16]=[CH:15][C:14]([NH:17]/[C:18](=[C:25]2\[C:26](=[O:37])[NH:27][C:28]3[C:33]\2=[CH:32][C:31]([N+:34]([O-:36])=[O:35])=[CH:30][CH:29]=3)/[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[CH:13][CH:12]=1)C)=O)(C)(C)C.C(OCC)(=O)C.[ClH:44]>>[ClH:44].[CH3:6][NH:8][CH2:10][C:11]1[CH:16]=[CH:15][C:14]([NH:17]/[C:18](=[C:25]2\[C:26](=[O:37])[NH:27][C:28]3[C:33]\2=[CH:32][C:31]([N+:34]([O-:36])=[O:35])=[CH:30][CH:29]=3)/[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 178482861HCID 178482861, compound

Product 1

HCID 178482860HCID 178482860, compound

Procedure

Prepared analogously to Example 29a from (Z)-3-{1-[4-(N-tert.butoxycarbonyl-N-methylamino)methyl-phenylamino]-1-phenyl-methylidene}-5-nitro-2-indolinone and ethyl acetate/hydrogen chloride.

Sources & evidence

ORD record
ord-6a92c1b2dcbd47d68a5c2f930b2b01b0
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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