Hydrogen chloride-ethyl acetate → HCID 178461846, compound

HRID 24837Notes

Reaction equation

HRID 24837 reaction equation
C(OC([NH:8][C@H:9]([C:11]1[CH:16]=[CH:15][C:14]([NH:17]/[C:18](=[C:25]2\[C:26](=[O:37])[NH:27][C:28]3[C:33]\2=[CH:32][C:31]([N+:34]([O-:36])=[O:35])=[CH:30][CH:29]=3)/[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[CH:13][CH:12]=1)[CH3:10])=O)(C)(C)C.C(OCC)(=O)C.[ClH:44]>>[ClH:44].[NH2:8][C@H:9]([C:11]1[CH:12]=[CH:13][C:14]([NH:17]/[C:18](=[C:25]2\[C:26](=[O:37])[NH:27][C:28]3[C:33]\2=[CH:32][C:31]([N+:34]([O-:36])=[O:35])=[CH:30][CH:29]=3)/[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[CH:15][CH:16]=1)[CH3:10]

Participants

3

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 178462192HCID 178462192, compound

Product 1

HCID 178461846HCID 178461846, compound

Procedure

Prepared analogously to Example 29a from (Z,S)-3-{1-[4-(1-tert.butoxycarbonylamino-ethyl)-phenylamino]-1-phenyl-methylidene}-5-nitro-2-indolinone and ethyl acetate/hydrogen chloride.

Sources & evidence

ORD record
ord-4bea710f01884468b5471bcdabb7668e
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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