HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Ethyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → HCID 19763562, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Ethyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | HCID 800521 | — |
| Reactant | HCID 19763584 | HCID 19763584 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 19763562 | HCID 19763562 | — |
Reaction Steps
A 1 g portion of 2-(1H-pyrrol-1-ylmethyl)piperazine and 0.76 g of 1-ethyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid were heated at 70°-75° C. in a sealed pressure bottle, filled with argon, for 18 hours, then ether was added and the solid collected, washed with ether and purified by chromatography, giving 595 mg of the desired product, mp 185°-188° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05210193 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-3e0459a088f04ed0ae7f9870341dbefa |
| Source note | uspto-grants-1993_05 |