2-[(Dodecyloxy)methyl]-1,4-bis(phenylmethyl)piperazine → HCID 19763547, compound

HRID 248507Notes

Reaction equation

HRID 248507 reaction equation
[CH2:1]([O:13][CH2:14][CH:15]1[CH2:20][N:19](CC2C=CC=CC=2)[CH2:18][CH2:17][N:16]1CC1C=CC=CC=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]>C(O)C.O.[Pd]>[CH2:1]([O:13][CH2:14][CH:15]1[CH2:20][NH:19][CH2:18][CH2:17][NH:16]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

5

Reactant 1

HCID 197635782-[(Dodecyloxy)methyl]-1,4-bis(phenylmethyl)piperazine

Product 1

HCID 19763547HCID 19763547, compound

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 702EthanolSolventHCID 962WaterSolvent

Procedure

An 8 g portion of the above piperazine in 130 ml of ethanol and 10 ml of water was hydrogenated with 10% palladium on carbon for 4 hours then filtered and the filtrate evaporated, giving 4.5 g of 2-[(dodecyloxy)methyl]piperazine.

Workup

  1. filtrationthen filtered
  2. customthe filtrate evaporated

Sources & evidence

ORD record
ord-10db5658fe564a03ab34b8adb2f7ad62
Source dataset
uspto-grants-1993_05
Patent number
US05210193

Reaction notes

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