HCID 19763605, compound → HCID 19763538, compound

HRID 248527Notes

Reaction equation

HRID 248527 reaction equation
[CH3:1][N:2]1[CH:6]=[CH:5][C:4]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][N:12]=2)=[N:3]1>[Pt]=O.CO>[CH3:1][N:2]1[CH:6]=[CH:5][C:4]([CH:7]2[NH:12][CH2:11][CH2:10][NH:9][CH2:8]2)=[N:3]1

Participants

4

Reactant 1

HCID 19763605HCID 19763605, compound

Product 1

HCID 19763538HCID 19763538, compound

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 887MethanolSolvent

Procedure

A 1.76 g portion of 3-(1-methyl-1H-pyrazol-3-yl)pyrazine and 0.5 g of platinum oxide catalyst in 75 ml of methanol was hydrogenated for 18 hours. The catalyst was removed and the filtrate evaporated, giving 1.8 g of 3-(1-methyl-1H-pyrazol-3-yl)piperazine.

Workup

  1. customThe catalyst was removed
  2. customthe filtrate evaporated

Sources & evidence

ORD record
ord-387cab419b3944d4bddf8be6cb209415
Source dataset
uspto-grants-1993_05
Patent number
US05210193

Reaction notes

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